Paraplegia due to missed thoracic meningioma after lumbar spinal decompression surgery: A case report and review of the literature

Spinal meningiomas are often localized to the thoracic level and symptoms from a spinal meningioma are determined by the location of the mass. We present a case of thoracic paraplegia due to a thoracic spinal cord tumor (meningioma) that was not detected during lumbar spinal decompressive surgery. Thoracic mass was detected in level of T2-3 on magnetic resonance imaging (MRI). The patient was re-operated and the patient's neurologic symptoms were partially relieved. Surgeons should know that a thoracic silent meningioma can aggrevate neurological symptoms after lumbar spinal decompression surgery and should inform their patient before surgery

STEM-Focused Activities to Support Student Learning in Primary School Science

This study examines the effect on student academic success through teaching the "Let's Know the Matter" grade 3 science unit accompanied by STEM (Science, Technology, Engineering, and Mathematics)-focused activities. The study group consisted of 24 third grade students studying in the 2019-2020 academic year. Teaching was done with a 5E (enter, explore, explain, elaborate, evaluate) instructional model, and student opinions about the STEM activities were collected. A group pretest-posttest research design was used in which the "Let's Know the Matter Test (MT)" was administered at the beginning to measure the students' prior knowledge, and again at the end of the unit to determine what students had learned. Their opinions of the lessons taught with STEM-focused activities were collected using a semi-structured interview technique. Qualitative data were divided into appropriate categories under common themes. It was observed that the 5E instructional model contributed to their academic success. Also, it was found that their opinions about the lessons taught with STEM activities were quite positive. Based on the results obtained from the research, it is suggested that STEM activities be used in the teaching of other topics

Giant cell tumor-like lesion of the urinary bladder: a report of two cases and literature review; giant cell tumor or undifferentiated carcinoma?

<p>Summary</p> <p>Giant cell tumor, excluding its prototype in bone, is usually a benign but local aggressive neoplasm originating from tendon sheath or soft tissue. Malignant behavior is uncommon. Visceral organ involvement including urinary bladder is rare. Giant cell tumors in visceral organs usually accompany epithelial tumors and the clinical behavior of giant cell tumor in urinary bladder is similar to its bone counterpart. Here, we report two cases of giant cell tumor located in urinary bladder in comparison with nine reported cases in the English literature. Concurrent noninvasive urothelial carcinoma was also described in all these previous reports and only one patient with follow-up died of disease. One of the two cases we present had no concurrent urothelial tumor at the time of diagnosis but had a history of a low grade noninvasive urothelial carcinoma with three recurrences. The histology of these two cases was similar to the giant cell tumor of bone and composed of oval to spindle mononuclear cells with evenly spaced osteoclast-like giant cells. Immunohistochemically, the giant cells showed staining with osteoclastic markers including CD68, TRAP, and LCA. Immunohistochemical expression of vimentin, CD68, LCA, and smooth muscle actin in mononuclear cells supported a mesenchymal origin with histiocytic lineage. The histologic and immunohistochemical properties in our cases as well as their clinical courses were consistent with a giant cell tumor. Consequently, tumors in urinary bladder showing features of giant cell tumor of bone may also be considered and termed "giant cell tumor".</p

COVID-19 in pediatric nephrology centers in Turkey

Background/aim: There is limited data on COVID-19 disease in children with kidney disease. We aimed to investigate the characteristics and prognosis of COVID-19 in pediatric nephrology patients in Turkey. Materials and methods: This was a national, multicenter, retrospective cohort study based on an online survey evaluating the data between 11th March 2020 and 11th March 2021 as an initial step of a detailed pediatric nephrology COVID-19 registry. Results: Two hundred and three patients (89 girls and 114 boys) were diagnosed with COVID-19. One-third of these patients (36.9%) were between 10–15 years old. Half of the patients were on kidney replacement therapy: kidney transplant (KTx) recipients (n = 56, 27.5%), patients receiving chronic hemodialysis (n = 33, 16.3%) and those on peritoneal dialysis (PD) (n = 18, 8.9%). Fifty-four (26.6%) children were asymptomatic. Eighty-two (40.3%) patients were hospitalized and 23 (28%) needed intensive care unit admission. Fifty-five percent of the patients were not treated, while the remaining was given favipiravir (20.7%), steroid (16.3%), and hydroxychloroquine (11.3%). Acute kidney injury developed in 19.5% of hospitalized patients. Five (2.4%) had MIS-C. Eighty-three percent of the patients were discharged without any apparent sequelae, while 7 (3.4%) died. One hundred and eight health care staff were infected during the study period. Conclusion: COVID-19 was most commonly seen in patients who underwent KTx and received HD. The combined immunosuppressive therapy and frequent exposure to the hospital setting may increase these patients’ susceptibility. Staff infections before vaccination era were alarming, various precautions should be taken for infection control, particularly optimal vaccination coverage

Risk factors associated with adverse fetal outcomes in pregnancies affected by Coronavirus disease 2019 (COVID-19): a secondary analysis of the WAPM study on COVID-19.

Objectives To evaluate the strength of association between maternal and pregnancy characteristics and the risk of adverse perinatal outcomes in pregnancies with laboratory confirmed COVID-19. Methods Secondary analysis of a multinational, cohort study on all consecutive pregnant women with laboratory-confirmed COVID-19 from February 1, 2020 to April 30, 2020 from 73 centers from 22 different countries. A confirmed case of COVID-19 was defined as a positive result on real-time reverse-transcriptase-polymerase-chain-reaction (RT-PCR) assay of nasal and pharyngeal swab specimens. The primary outcome was a composite adverse fetal outcome, defined as the presence of either abortion (pregnancy loss before 22 weeks of gestations), stillbirth (intrauterine fetal death after 22 weeks of gestation), neonatal death (death of a live-born infant within the first 28 days of life), and perinatal death (either stillbirth or neonatal death). Logistic regression analysis was performed to evaluate parameters independently associated with the primary outcome. Logistic regression was reported as odds ratio (OR) with 95% confidence interval (CI). Results Mean gestational age at diagnosis was 30.6+/-9.5 weeks, with 8.0% of women being diagnosed in the first, 22.2% in the second and 69.8% in the third trimester of pregnancy. There were six miscarriage (2.3%), six intrauterine device (IUD) (2.3) and 5 (2.0%) neonatal deaths, with an overall rate of perinatal death of 4.2% (11/265), thus resulting into 17 cases experiencing and 226 not experiencing composite adverse fetal outcome. Neither stillbirths nor neonatal deaths had congenital anomalies found at antenatal or postnatal evaluation. Furthermore, none of the cases experiencing IUD had signs of impending demise at arterial or venous Doppler. Neonatal deaths were all considered as prematurity-related adverse events. Of the 250 live-born neonates, one (0.4%) was found positive at RT-PCR pharyngeal swabs performed after delivery. The mother was tested positive during the third trimester of pregnancy. The newborn was asymptomatic and had negative RT-PCR test after 14 days of life. At logistic regression analysis, gestational age at diagnosis (OR: 0.85, 95% CI 0.8-0.9 per week increase; pPeer reviewe

Maternal and perinatal outcomes of pregnant women with SARS-CoV-2 infection

Objectives To evaluate the maternal and perinatal outcomes of pregnancies affected by SARS-CoV-2 infection. Methods This was a multinational retrospective cohort study including women with a singleton pregnancy and laboratory-confirmed SARS-CoV-2 infection, conducted in 72 centers in 22 different countries in Europe, the USA, South America, Asia and Australia, between 1 February 2020 and 30 April 2020. Confirmed SARS-CoV-2 infection was defined as a positive result on real-time reverse-transcription polymerase chain reaction (RT-PCR) assay of nasopharyngeal swab specimens. The primary outcome was a composite measure of maternal mortality and morbidity, including admission to the intensive care unit (ICU), use of mechanical ventilation and death. Results In total, 388 women with a singleton pregnancy tested positive for SARS-CoV-2 on RT-PCR of a nasopharyngeal swab and were included in the study. Composite adverse maternal outcome was observed in 47/388 (12.1%) women; 43 (11.1%) women were admitted to the ICU, 36 (9.3%) required mechanical ventilation and three (0.8%) died. Of the 388 women included in the study, 122 (31.4%) were still pregnant at the time of data analysis. Among the other 266 women, six (19.4% of the 31 women with first-trimester infection) had miscarriage, three (1.1%) had termination of pregnancy, six (2.3%) had stillbirth and 251 (94.4%) delivered a liveborn infant. The rate of preterm birth before 37 weeks' gestation was 26.3% (70/266). Of the 251 liveborn infants, 69/251(27.5%) were admitted to the neonatal ICU, and there were five (2.0%) neonatal deaths. The overall rate of perinatal death was 4.1% (11/266). Only one (1/251, 0.4%) infant, born to a mother who tested positive during the third trimester, was found to be positive for SARS-CoV-2 on RT-PCR. Conclusions SARS-CoV-2 infection in pregnant women is associated with a 0.8% rate of maternal mortality, but an 11.1% rate of admission to the ICU. The risk of vertical transmission seems to be negligible. (C) 2020 International Society of Ultrasound in Obstetrics and Gynecology.Peer reviewe

Aproposal on the restoration and refunctioning of Taş Han in Bartın city center

Bu çalışma Bartın'da yer alan geleneksel ticari yapılardan, Taş Han'ı konu etmektedir. Çalışmanın amacı, hanın rölöve projesinin hazırlanarak, mevcut durumun değerlendirilmesi, restitüsyon çalışmasının yapılarak özgün durumun belirlenmesi ve geçirdiği değişikliklerin tespit edilmesi, ortaya çıkan restitüsyon projesinin ışığında, yeniden ticari yapı işleviyle restorasyon projesinin yapılmasıdır. Böylece han, restorasyon projesine göre onarımı yapılarak yeniden işlevlendirildikten sonra, tekrar kullanılmaya başlanacak ve bu kültür varlığımız gelecek nesillere sağlıklı olarak aktarılabilecektir.Taş Han, one of the traditional commercial building of Bartın, is the subject of the study. The aim of the study is; to prepare the measured drawings and to document the present situation, to determine the original situation via restitution project, and find out the alterations, with the assistance of the restitution project to mantain a restoration project with commercial building function. Thus the building can be conserved and functioned as a commercial building, which is close to it's original function. By this way this culturel heritage can be transfered to the future generations

İlkokul fen bilimleri dersi öğretim programı öğelerinin inovatif düşünce açısından incelenmesi

İlkokul düzeyinde 3. ve 4. sınıflarda, ortaokul düzeyinde ise 5, 6, 7 ve 8. sınıflarında okutulan fen bilimleri dersinde öğrencilere keşfetme, sorgulama, yeni teknolojiler üretebilme, doğaya karşı meraklı olabilme, fen ve mühendislik uygulamaları hakkında temel bilgi sahibi olabilme gibi birçok becerinin kazandırılması hedeflenmektedir. Fen bilimleri dersinin becerilerinden biri olan inovatif düşünme becerisi ile öğrencilere farklı, değişik fikirler üreterek bu düşüncelerini uygulayabilme ve inovatif düşünme becerisini hayatlarına taşıma fırsatı sunulmaktadır. Bu anlamda ilkokul fen bilimleri dersi öğretim programının temel öğelerini ve kazanımlarını, 21.yüzyıl becerilerinden biri olan inovasyon açısından değerlendirmek ve çıkan sonuçları incelemek önemlidir. Araştırmanın temel amacı, ilkokul fen bilimleri dersi öğretim programı öğelerini inovatif düşünce açısından incelemektir. Çalışmanın veri kaynaklarını ilkokul fen bilimleri dersi öğretim programı oluşturmaktadır. Dersin öğretim programındaki özel amaçlarda, bireylerin karşılaştıkları sorunlara inovatif çözümler üretebilmelerinin hedeflendiği görülmüştür. Öğrencilere bilgiyi ürüne dönüştürme rolleri; öğretmenlere ise öğrencilerin ürün geliştirmelerine, buluş ve inovasyon yapabilmelerine rehberlik edecekleri roller tanımlanmıştır. Önerilen strateji ve yöntemlerde, öğrencilerin yaratıcı düşünme becerisi yönünden geliştirilmesine olanak sağlayan araştırma ve sorgulamaya dayalı öğrenme stratejisinin benimsendiği görülmüştür. Programdaki fen, mühendislik ve girişimcilik uygulamaları ile inovatif düşünme becerisi kazanan öğrencilerin, inovatif mühendislik üzerine buluşlar yapmaları hedeflenmektedir

Determining the prevalence of obesity in primary school students and eating habits in Izmir

AbstractObjective: This study examined the prevalance of obesity in primary school students in Güzelbahçe, eating habits and parents’ opinion about “Nutrition-Friendly School Project”. Methods: This is a cross-sectional study. 549 children are taken to the study having education in primary schools in Güzelbahçe. Study was conducted in two public and two private schools between March-May 2012 in Güzelbahçe. We reached 549 students. The dependent variable is obesity conditions determined according to BMI. The independent variables are socio-demographic attributes, kind of school, food habits, physical activity, watching TV and computer usage and frequency of food consumption. In the research, a questionnaire was applied to student’s parents in relation with independent variables and applied to students in relation with the food consumption. Height and weight of students were measured and BMI was calculated. Chi-square analysis and logistic regression were used for statistical analysis. OR’s were calculated for factors that cause obesity. Results: Prevalence of obesity was 20% in the study. There is a significant higher obesity in boys than girls. Prevalence of obesity was significantly higher in higher education of mothers. There is no significant relationship between school type and eating habits and obesity. Most consumed food from the canteen by student; chocolate, fries and cornflakes. Most consumed drinks are milk, ayran and fruit juice. Parents of support this project 95.9% and most parents think that there will be a decrease in obesity for Project 89.1%. Conclusions: Higher education of mothers and higher monthly income is associated with obesity of children. Mothers can be given education about nutrition at home and healthy food preparation. Physical activity in children should be increased.Key Words: Obesity, BMI, primary education, eating habits, nutrition-friendly school project.</p